vhl ligand 3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17877	VH032-cyclopropane-F	VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101	Others , Ligand for E3 Ligase
	VH032-cyclopropane-F (Phenolic VH101) is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.		Others , Ligand for E3 Ligase
T17924	(S,R,S)-AHPC-PEG2-NH2 hydrochloride	VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit...		Others , E3 Ligase Ligand-Linker Conjugate
T17922	(S,R,S)-AHPC-PEG3-NH2 hydrochloride	VHL Ligand-Linker Conjugates 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 5,VH032-PEG3-NH2 hydrochloride,VHL Ligand-Linker Conjugates 1 HCl	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligand and 3-unit PEG linker.		Others , E3 Ligase Ligand-Linker Conjugate
T17920	(S,R,S)-AHPC-PEG1-N3	VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG1-N3 incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC tec...		Others , Ligand for E3 Ligase
T17909	(S,R,S)-AHPC-PEG3-N3	VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12	Others , E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase
	(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC tec...
T17925	(S,R,S)-AHPC-PEG2-NH2	VH032-PEG2-NH2,VHL Ligand-Linker Conjugates 3,E3 ligase Ligand-Linker Conjugates 6 Free Base	Others , E3 Ligase Ligand-Linker Conjugate
	(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis ...		Others , E3 Ligase Ligand-Linker Conjugate
T17912	(S,R,S)-AHPC-(C3-PEG)2-C6-Cl	VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11	Others
	(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-Ha...		Others
T17923	(S,R,S)-AHPC-PEG3-NH2	E3 ligase Ligand-Linker Conjugates 5 Free Base,VH032-PEG3-NH2,VHL Ligand-Linker Conjugates 1	Others
	(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology.		Others
T5437	Gefitinib-based PROTAC 3		EGFR , PROTACs
	Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectivel...		EGFR , PROTACs
T36268	VH 032 Linker 3 (hydrate)
	VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 . N/A
T18610	PROTAC FKBP Degrader-3		Others , PROTACs
	PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an VHL binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].		Others , PROTACs
T60251	GID4 Ligand 3
	GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC 50 value of 148.5 μM. GID4 Ligand 3 can be used in the relevant research of cereblon(CRBN) and Von Hippel-Lindau(VHL) [1].
T39494	(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH	VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH,(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
	(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, also known as VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and, on one end, features a...
T41173	FAM-DEALAHypYIPMDDDFQLRSF
	FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluor...
T18056	K-Ras ligand-Linker Conjugate 3		Others
	K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). ...		Others
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl	VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8	Others
	(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in ce...		Others